Afatinib dimaleate is a prescription anti-cancer medicine used in the treatment of non-small cell lung cancer (NSCLC). It is used in people with metastatic non-small cell lung cancer that has an abnormal EGFR gene (epidermal growth factor receptor). This medication will be prescribed for the 1st time or if the previous treatment did not work well for you.
Non-small cell lung cancer is one of the two major types of lung cancer and accounts for around 80 to 85% of lung cancer cases. This cancer begins when healthy cells in the lungs change and grow in an uncontrolled manner. When cancer grows, it may shed cancer cells, and these cells can spread to nearby tissues or other parts of the body and this stage is called metastatic. Most commonly, this cancer spreads to other parts of the lungs, lymph nodes, brain, bones, liver and structures near the kidneys. There are many subtypes of NSCLC, and the main subtypes include squamous cell carcinoma, adenocarcinoma, and large cell carcinoma. Smoking is the leading cause of lung cancer. Smoking can damage the cells lining the lungs, and over time, this damage may lead to lung cancer. This cancer can also occur in people who never smoked, and the risk factors include exposure to secondhand smoke, radiation exposure, family history of lung cancer, and exposure to certain substances (such as arsenic, nickel, chromium) in the workplace and having HIV infection. People with NSCLC may experience shortness of breath, tiredness, coughing up blood or mucus, unintentional weight loss, appetite loss, hoarseness, chest pain, and cough. Metastatic NSCLC can cause symptoms such as bone pain, back pain, speech difficulties, seizures, and excessive breathing difficulties. For people who have no symptoms, cancer may be found on an imaging test such as a CT scan done for some other reason. Afatinib dimaleate is a targeted therapy drug where it precisely identifies and attacks specific genes and proteins involved in cancer development, thus leading to fewer side effects. A group of proteins called the ErbB family are involved in the spread and growth of cancer cells in NSCLC. Afatanib dimaleate blocks the activity of these proteins and stops the growth and spread of cancer cells. This drug should not be consumed by pregnant or breastfeeding women. To avoid becoming pregnant, it is important to use effective birth control during the treatment and for at least one month after the treatment. Without the doctor’s approval, do not receive any vaccinations or immunizations while taking afatinib dimaleate. This medication can make the skin sensitive to sunlight and may cause severe sunburn or worsening acne on too much exposure. You should use sunscreen and wear sun protective clothing outdoors while on this medication Your physician will determine your exact afatinib dosage and schedule based on your general health, type of cancer, and many other factors. Xovoltib 30mg Tablet is one of the products containing this active constituent, and your doctor may prescribe this medication if you have NSCLC.
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